Today we follow the path of the mighty Mississippi River and travel deep into the heart of the Mississippi Delta, the “Birthplace of the Blues.” From the cotton fields, street corners, and juke joints of the Mississippi Delta came a new kind of music—the blues. Considered by many to be the only truly indigenous American music, the blues has influenced musicians worldwide. Blues legends such as Muddy Waters, Sam Cooke, Ike Turner, and John Lee Hooker honed their incredible music talents here before sharing them with the world. Visit the DELTA BLUES MUSEUM, dedicated to exploring the history and heritage of this unique American musical art form. Exhibits contain historical images, artifacts, musical instruments, and the remains of the cabin where Muddy Waters lived during his days as a sharecropper. Enjoy an orientation tour of some of Clarksdale’s famous blues sites, including a photo stop at the “Cross Roads,” where legendary blues guitarist Robert Johnson sold his soul to the devil to play like no one else. Then, a special lunch at Ground Zero Blues Club, owned by Academy Award-winning actor Morgan Freeman. Enjoy some downhome Southern cooking before continuing to Greenwood, where many of the city’s downtown buildings are listed on the National Register of Historic Places. (Breakfast, Lunch)SPECIAL FEATURE: Overnight at the historic Alluvian Hotel. Originally opened in 1917, it has undergone a major transformation, and is now rated as one of the Top 10 Hotels in the United States by Conde Nast magazine.